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Ryan Smith, DDS

Clinical · Anesthesia and sedation

The modified Mallampati classification: four classes, and a screen that misses about half of difficult intubations

Mallampati's 1985 study of 210 patients graded the view of the faucial pillars, soft palate and uvula in three classes; Samsoon and Young added a fourth in 1987 and a class 0 arrived in 1998. The Cochrane review of 133 studies puts the modified test at a summary sensitivity of 0.51 and specificity of 0.87 for difficult tracheal intubation.

Clinical guidelines and evidence

Issued by

StatPearls, NCBI Bookshelf; classification from Mallampati et al. (1985) as modified by Samsoon and Young (1987)

1987

Status
current
Source
ncbi.nlm.nih.gov
Last read
2026-09-13
Five tiles in a row for the modified Mallampati classes. Class 0: epiglottis partially or fully visible, added in 1998 and rare. Class I: soft palate, uvula and tonsillar pillars all in full view. Class II: soft palate and uvula visible, pillars obscured. Class III: soft palate and the base of the uvula visible. Class IV: hard palate only. A band beneath, marked in coral, reports the Cochrane summary sensitivity of 0.51 for difficult tracheal intubation with specificity 0.87, drawn from 105 studies of the modified test inside a review of 133 studies and 844,206 participants, and notes that sensitivity for difficult mask ventilation was 0.17 and that reported positive predictive values run as low as 22 to 33 percent.
The classes as the StatPearls chapter states them, with the examination they depend on and the pooled accuracy from the Cochrane review. Wording condensed. Illustration, not clinical advice.Open full size
classes in the modified score, I through IV, with a class 0 added in 1998 for a visible epiglottis
4
summary sensitivity of the modified test for difficult tracheal intubation in the Cochrane review; specificity 0.87
0.51
patients in Mallampati's 1985 prospective study, the paper that introduced the sign in three classes
210
summary sensitivity of the modified test for predicting difficult face mask ventilation
0.17

Covered

3
  • Any patient being evaluated before anesthesia or intubation: StatPearls says the score is used when a patient requires anesthesia or intubation, to anticipate airway anatomy challenges before securing the airway
  • Cooperative adults who can sit upright, open fully and protrude the tongue, which is the examination the score is defined by
  • Obstructive sleep apnea risk: the score is described as an independent predictor of the presence and severity of OSA, with the odds doubling for every one-point increase in class

Not covered

3
  • Patients who cannot cooperate with the examination: the chapter says the score's usefulness diminishes, though it lists no absolute contraindication
  • Airways made difficult by pathology rather than tongue size: head and neck infections and cancers, epiglottitis, Ludwig angina, goiter and facial trauma are named as causes the score cannot accurately predict
  • Dental sedation rules: the ADA's October 2025 sedation guidelines, read for this entry, never name the Mallampati score, and nothing in these sources sets a class that permits or forbids office sedation

Timeline

  1. 1983

    1. May

      Mallampati publishes the hypothesis that tongue base size relative to the oropharyngeal cavity predicts difficult intubation (Can Anaesth Soc J 30(3 Pt 1):316-7)

  2. 1985

    1. Jul

      Mallampati and colleagues test it in 210 patients and describe three classes (Can Anaesth Soc J 32(4):429-434)

  3. 1987

    1. May

      Samsoon and Young add the fourth class in a retrospective study; failed intubation occurred in 7 of 1980 obstetric cases and 6 of 13,380 surgical cases (Anaesthesia 42(5):487-490)

  4. 1998

    1. Sep

      Ezri and colleagues describe class 0, the rare case where the epiglottis is visible on pharyngoscopy

  5. 2018

    1. May 15

      Cochrane review of airway physical examination tests, 133 studies and 844,206 participants, concludes the bedside tests are not good screening tests

  6. 2025

    1. Jul 7

      Last update of the StatPearls chapter that this entry reports

    2. OctLatest

      ADA Guidelines for the Use of Sedation and General Anesthesia by Dentists adopted; the pre-procedural workup they name is ASA class, physician consultation for ASA III and IV, and body mass index, with no mention of the Mallampati score

What it says

The score exists because of one idea: that the size of the base of the tongue, relative to the space it sits in, decides how much of the larynx a laryngoscopist will be able to see. Mallampati proposed it in 1983 and tested it in 1985 in 210 healthy adults. The examination he described is the one still used. The patient sits, opens the mouth fully and protrudes the tongue maximally, without phonation, and the examiner records which structures remain visible. Three classes came out of it: class I, complete visualization of the faucial pillars, soft palate and uvula; class II, the faucial pillars and soft palate visible with the uvula obscured by the tongue base; class III, visualization limited to the soft palate alone. Mallampati defined difficult intubation as inadequate exposure of the glottis at direct laryngoscopy and reported a significant correlation (p less than 0.001).

Two years later Samsoon and Young added the class that made it a four-point scale: a view in which the faucial pillars, uvula and soft palate are all obscured. Their paper was a retrospective look at patients whose tracheas had previously been impossible to intubate; failed intubation occurred in 7 of 1980 obstetric cases over 3 years and in 6 of 13,380 surgical patients, and in their obstetric series all 7 difficult intubations corresponded to class III or IV. In 1998 a class 0 was added for the rare case in which the epiglottis is visible during pharyngoscopy, a finding that correlated with consistently easy intubation.

The modified score in routine use today, as StatPearls states it: class 0, epiglottis partially or fully visible; class I, full view of soft palate, uvula and tonsillar pillars; class II, soft palate and uvula visible, pillars obscured; class III, soft palate and uvula base visible; class IV, visualization restricted to the hard palate. An extended version, performed with the craniocervical junction extended, has been reported to have greater sensitivity and specificity than the modified test.

The accuracy is the part that gets left out of the training video. The Cochrane review of airway physical examination tests, 133 studies and 844,206 participants, found 105 studies of the modified Mallampati test. For difficult tracheal intubation, its summary sensitivity was 0.51 (95% CI 0.40 to 0.61) with a specificity of 0.87 (0.82 to 0.91); that sensitivity was the highest of the bedside tests for this target, which says as much about the other tests as about this one. For difficult laryngoscopy, the modified test had the lowest specificity in the set, 0.80 (0.74 to 0.85). For difficult face mask ventilation it could only be estimated at a sensitivity of 0.17 (0.06 to 0.39) and specificity of 0.90 (0.81 to 0.95). The reviewers' conclusion is that screening tests are expected to have high sensitivities, that all the tests they investigated had relatively low sensitivities with high variability, and that the upper lip bite test had the most favorable properties of the group.

The older literature points the same way. Positive predictive values as low as 33.3% have been reported, and 22% for class III specifically, in part because views the Mallampati system calls difficult often turn out to be favorable under the Cormack-Lehane grading of the actual laryngoscopic view. StatPearls adds the context that difficulty is common enough to matter, roughly 1% to 5% of patients are difficult to mask ventilate and around 5% are difficult to intubate, and that in a large cohort 93% of difficult intubations and 94% of difficult mask ventilations were unanticipated.

Two findings travel beyond the operating room. In 242 pregnant patients the proportion classified class IV rose by 34% at 38 weeks compared with the same women at 12 weeks, attributed to fluid retention and soft tissue edema. And the score is an independent predictor of obstructive sleep apnea, with the odds of OSA doubling for every one-point increase in class and the apnea-hypopnea index rising by more than 5 events per hour on average.

From the document

The standard bedside airway examination tests should be interpreted with caution, as they do not appear to be good screening tests.
Authors' conclusions, Cochrane Database Syst Rev 2018;5:CD008874

Who it applies to

Anyone evaluating a patient before sedation, anesthesia or intubation, in a dental office or anywhere else, who can get the patient to sit up, open wide and stick out the tongue. It is a 10-second observation with no equipment, which is exactly why it spread.

It does not apply cleanly to a patient who cannot cooperate, and it does not see the airway made difficult by disease rather than anatomy: infections and tumors of the head and neck, epiglottitis, Ludwig angina, goiter and facial trauma are named as conditions whose difficulty the score cannot predict. It is also not the same thing as the Cormack-Lehane grade, which describes what the laryngoscopist actually sees, and it is not a rule in dentistry. The ADA's October 2025 sedation guidelines, read in full for this entry, never mention it; the pre-procedural evaluation they describe runs on ASA physical status, consultation with the physician for ASA III and IV patients, and body mass index.

What changed

Nothing about the classes has changed since 1998. What has changed is the claim made for them. The score entered practice as a predictor; the meta-analytic work of the last twenty years has demoted it to one risk factor among several, to be read next to neck circumference over 40 cm, limited neck mobility, mouth opening under three finger breadths, thyromental distance under 6 cm, limited mandibular protrusion and a documented history of a difficult airway. StatPearls states the current position plainly: the score alone lacks sufficient sensitivity to identify patients with challenging airways, and reliance on it in isolation is not advised.

What to do in the practice

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Where the source is

The link under the title opens the StatPearls chapter Mallampati Score, by James S. Jackson and Bryan Rondeau, on the NCBI Bookshelf (Bookshelf ID NBK585119), last updated July 7, 2025 and distributed under a CC BY-NC-ND 4.0 license; it was read in full for this entry and is the source of the class definitions, the examination technique and the historical sequence. The two original papers are cited above and were read as PubMed abstracts: Mallampati and colleagues, Canadian Anaesthetists' Society Journal 1985, and Samsoon and Young, Anaesthesia 1987; both journals are behind paywalls, so the class definitions here are as StatPearls states them, not transcribed from the originals. The accuracy figures come from the Cochrane review by Roth and colleagues, CD008874, whose abstract and authors' conclusions were read on PubMed and whose full text is free in PubMed Central. The statement that the ADA's sedation guidelines do not use the score is based on a full-text search of the ADA's October 2025 guidelines PDF, linked above.

sedationanesthesiarisk assessmentmedical historyscreeningtoolsleep apneaphysician referral

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